Association of glycemic and lipid markers with fall risk, kinesiophobia and cardiopulmonary endurance in post-stroke diabetic patients
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Abstract
Objectives: To determine the relationship between glycemic control (HbA1c, blood sugar random [BSR]) and serum triglycerides with risk of falls, kinesiophobia, and cardiopulmonary endurance in post-stroke diabetic patients.
Methods: This correlational study was conducted from June 2022 to July 2023 at The Diabetic Centre, Pakistan Institute of Medical Sciences, Islamabad. A total of 226 post-stroke diabetic patients of both genders were recruited through non-probability purposive sampling. Assessments included glycemic and lipid profiles, the Tampa Scale for kinesiophobia, the six-minute walk test, and the timed up-and-go test. The age range of 45 to 85 years was considered, including individuals who had recovered from stroke, excluding those with hematological disorders, co-morbidities, or neurological complications. For statistical analysis, Pearson correlational performed using SPSS-21.
Results: Out of the 226 subjects, 54% were female and 46% were male, with a mean age of 61±10 years and a mean body mass index of 24.8±5.26 kg/m2. Serum triglyceride levels showed a negligible and non-significant correlation with the risk of falls and kinesiophobia (r=0.088, r=0.096; p>0.05, respectively), but a negligible negative relationship with cardiopulmonary endurance (r= -0.09; p < 0.05). Blood sugar random demonstrated a negative moderate relation with cardiopulmonary endurance (r= -0.3; p<0.05). HbA1c exhibited a moderate negative correlation with cardiopulmonary endurance (r= -0.50; p <0.05).
Conclusion: Among post-stroke diabetic patients, poor glycemic control, particularly elevated HbA1c, was significantly associated with higher fall risk, increased kinesiophobia, and reduced cardiopulmonary endurance. Routine monitoring and optimization of HbA1c may be critical in mitigating functional decline in this population.
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