PREDICTORS OF GESTATIONAL DIABETES MELLITUS: STUDY CONDUCTED IN PUBLIC AND PRIVATE HEALTH CARE CENTRES OF PESHAWAR

ayesha zakir, Farhat Shehzad, Rubina Nazli

Abstract


AUTHORS: Ayesha Zakir, Dr. Farhat Shehzad, Dr. Rubina Nazli

ABSTRACT

Objective: The objective of the study was to determine the predictors of gestational diabetes mellitus (GDM).

Method: This study was conducted in the Khyber teaching hospital, Health care center, Kalsoom maternity home Peshawar. The targeted population was the registered cases of pregnant women with Gestational Diabetes Mellitus (GDM). Data was collected through questionnaire and antenatal cards of the gestational diabetic patients.

Results:  64 observed patients were > 30 years of age, 67 patients had BMI greater than 25, and 71 patients showed a strong family history of diabetes mellitus. 73 patients were found multiparous and 66 patients suffered from GDM in their previous pregnancies.

Conclusion: According to the results, advanced maternal age i.e. above 30 years, multiparity, and family history of diabetes mellitus were found to be the strong predictors of GDM. Whereas greater BMI and previous history of GDM along with the strong predictors of GDM can adverse the situation.

Key words: GDM, Maternal age > 30years, Multiparity, BMI > 25, Strong genealogy of Diabetes mellitus, and GDM history.


References


REFERENCES

Aberg A, Westbom L, Kallen B. congenital malformations among infants whose mothers had gestational diabetes or preexisting diabetes. Early Hum DEV. 2001 Mar: 61(2): 85-95.

Ben-Haroush A, Yogev Y, Hod m. epidemiology of gestational diabetes mellitus and its association with Type 2 diabetes. Diabet Med. 2004 Feb: 21(2): 103-13.

Bennewitz H. De diabete mellito, graviditatis symptomate, in University of Berlin. 1824.

Branchtein L, Schmidt MI, Matos MC, Yamashita T, Pousada JM, Duncan BB. Short stature and gestational diabetes in Brazil. Brazilian Gestational Diabetes Study Group. Diabetologia. 200 Jul: 43(7):848-51.

Buchanan TA, Xiang AH. Gestational diabetes mellitus. J Clin Invest. 2005 Mar: 115(3): 485-91.

Carr DB, Gabbe S (1998). Gestational Diabetes: Detection, Management, and Implications. Clin Diabetes 16(1):4.

Cnattinguis S, Lambe M. Trends in smoking and overweight during pregnancy: prevalence, risks of pregnancy complications and adverse pregnancy outcomes. Semin Perinatol. 2002 Aug: 26(4): 286-95.

Cypryk K, Szymczak W, Czupryniak L, Sobczak M, Lewinski A. gestational diabetes mellitus- an analysis of risk factors. Endokrynol Pol. 2008 Sep-Oct: 59(5): 393-7.

De Valk HW, Visser GHA: Insulin During Pregnancy, Labor and Delivery. Best Pract Res Clin Obstet Gynaecol 2011; 25(1): 65-76.

Duncan M. On puerperal diabetes. Trans Obstet Soc London, 1882; 24: p: 256-285.

Harder T, Franke K, Kohlhoff R, Plagemann A. Maternal and paternal family history of diabetes in women with gestational diabetes or insulin dependent diabetes mellitus type 1. Gynaecol Obstet Invest. 2005; 51(3): 160-4.

Jackson W.P. Studies in prediabetes. Br Med J, 1952; 2(4786): P. 690-6.

Khan A, Jaffery SN. Screening for gestational diabetes. Medical Channel 1997; 3: 8-12.

Kousta E, Cela E, Lawrence N, Penny A, Millauer B, White D. The prevalence of polycystic ovaries in women with a history of gestational diabetes. Clin Endocrinol (Oxf). 2000 Oct; 53(4): 501-7.

Langer O, Yogev Y, Xenakis EM, Brustman L. Overweight and obese in gestational diabetes: the impact on pregnancy outcome. Am J Obstet Gynaecol. 2005 Jun; 192(6): 1768-76.

Nassar AH, Fayyumy R, Saab W, Mehio G, Usta IM. Grandmultiparas in modern obstetrics. Am J Perinatol. 2006 Aug; 23(6): 345-9.

Nobile de Santis MS, Radaelli T, Tarrico E, Bertini S, Cetin I. Excess of amniotic fluid: pathophysiology, correlated diseases and clinical management. Acta Biomed. 2004; 75 Suppl 1:53-5.

Ostlund I, Hanson U, Bjorklund A, Hjertberg R, Eva N, Nordlander E. Maternal and fetal outcomes if gestational impaired glucose tolerance is not treated. Diabetes Care. 2003 Jul; 26(7): 2107-11.

O’Sulliven J.B. Gestational diabetes. Unsuspected, asymptomatic diabetes in pregnancy. N Engl J Med, 1961. 264: p. 1082-5.

Radhia Khan, Khurshid Ali and Zakkia Khan. Socio-demographic risk factors of gestational diabetes mellitus. Pak J Med Sci. 2013 May-Jun; 29(3): 843-846.

Randhawa MS, Moin S, Shoaib F. Diabetes mellitus during pregnancy: a study of fifty cases. Pak J Med Sci. 2003; 19: 277-82.

Roman H, Robillard PY, Verspyck E, Hulsey TC, Marpeau L, Barau G. Obstetric and neonatal outcomes in grand multiparity. Obstet Gynaecol. 2004 Jun; 103(6): 1294-9.

Simmons D, Thompson CF, Conroy C. Incidence and risk factors for neonatal hypoglycemia among women with gestational diabetes mellitus in South Auckland. Diabet Med. 2000 Dec; 17(12): 830-4.

Weiss JL, Malone FD, Emig D, Ball RH, Nyberg DA, Comstock CH. Obesity, obstetric complications and cesearian delivery rate- a population based screening study. Am J Obstet Gynaecol. 2004 Apr; 190(4): 1091-7.

Wilkerson H.L. and Remein Q.R. Studies of abnormal carbohydrate metabolism in pregnancy; the significance of impaired glucose tolerance. Diabetes, 1957. 6()4 : 324-9.

Yang X, Hsu-Hage B, Zhang H, Zhang C, Zhang Y, Zhang C. Women with impaired glucose tolerance during pregnancy have significantly poor pregnancy outcomes. Diabetes Care. 2002 Sep; 25(9): 1619-24.




KHYBER MEDICAL UNIVERSITY (KMU) PESHAWAR

KMU INSTITUTE OF MEDICAL SCIENCES (KIMS), KOHAT, KHYBER PAKHTUNKHWA, PAKISTAN- 2012

 

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