Self-medication practices and their relationship with the psychological wellbeing in university employees of Saudi Arabia: a cross-sectional study

Main Article Content

Syed Shahid Habib
Thamir Al-Khlawi
Abdullah Almushawah
Abdulaziz Hassan Alsomali
Syed Mohammad Habib
Huthayfah Al-khliwi

Abstract

Objective: To determine the prevalence of depression, anxiety, and stress (DAS) and their association with self-medication (SM) practices among university employees in Saudi Arabia, along with the key sociodemographic determinants.


Methods: This cross-sectional study was conducted using a self-administered online survey from July 2022 to June 2023. A total of 383 university employees from Riyadh, Saudi Arabia, were included through non-probability sampling. Data were collected on sociodemographic variables, self-medication behavior, and psychological distress using validated DAS Scale (DASS-21). SM practices were analyzed in relation to DAS scores using descriptive statistics, Chi-square tests, t-tests, and univariate logistic regression.


Results: Among 383 participants, 71% were male. Prevalence of self-medication (SM) was 60.8%. Overall, 25.1% of participants exhibited symptoms of depression, 39% had anxiety, and 21.9% reported stress.  Among individuals who were engaged in SM, the prevalence of depression was 16.2% (n=62), anxiety 27.7% (n=106), and stress 15.1% (n=58). Anxiety showed a significant association with SM (p=0.002), while depression (p=0.669) and stress (p=0.087) did not. Mean anxiety (8.34 vs. 5.79; p=0.002) and stress scores (9.28 vs. 6.97; p=0.013) were significantly higher in SM users. Univariate regression revealed that moderate anxiety was strongly associated with SM (OR=3.6; 95% CI: 1.77–7.29; p=0.003). No significant associations were observed for depression or stress.


Conclusion: Self-medication is common among university employees in Saudi Arabia and is significantly associated with anxiety, particularly at moderate levels. These findings emphasize the need for awareness programs addressing mental health and the risks associated with unsupervised medication use, particularly in academic settings.

Article Details

How to Cite
Habib, Syed Shahid, et al. “Self-Medication Practices and Their Relationship With the Psychological Wellbeing in University Employees of Saudi Arabia: A Cross-Sectional Study”. KHYBER MEDICAL UNIVERSITY JOURNAL, vol. 17, no. 2, June 2025, pp. 130-6, doi:10.35845/kmuj.2025.23621.
Section
Original Articles

References

1. Fadhel F. Misuse of prescription drugs and other psychotropic substances among university students: a pilot study. East Mediterr Health J 2022;28(4):288-95. https://doi.org/10.26719/emhj.22.019

2. Wijesinghe PR, Jayakody RL, de A Seneviratne R. Prevalence and predictors of self-medication in a selected urban and rural district of Sri Lanka. WHO South East Asia J Public Health 2012;1(1):28-41. https://doi.org/10.4103/2224-3151.206911

3. National Collaborating Centre for Mental Health (UK). Drug misuse: psychosocial interventions. Leicester (UK): British Psychological Society (UK); 2008. (NICE Clinical Guidelines, No. 51.) 3, Introduction to drug misuse. Available from URL: https://www.ncbi.nlm.nih.gov/books/NBK53217/

4. Harris KM, Edlund MJ. Self-medication of mental health problems: new evidence from a national survey. Health Serv Res 2005;40(1):117-34. https://doi.org/10.1111/j.1475-6773.2005.00345

5. Nochaiwong S, Ruengorn C, Thavorn K, Hutton B, Awiphan R, Phosuya C, et al. Global prevalence of mental health issues among the general population during the coronavirus disease-2019 pandemic: a systematic review and meta-analysis. Sci Rep 2021;11(1):10173. https://doi.org/10.1038/s41598-021-89700-8

6. Patwary MM, Bardhan M, Disha AS, Kabir MP, Hossain MR, Alam MA, et al. Mental health status of university students and working professionals during the early stage of COVID-19 in Bangladesh. Int J Environ Res Public Health 2022;19(11):6834. https://doi.org/10.3390/ijerph19116834

7. Mkumbo KA. Prevalence of and factors associated with work stress in academia in Tanzania. Int J Higher Edu 2014;3(1):1-11. https://doi.org/10.5430/ijhe.v3n1p1

8. Marijanović I, Kraljević M, Buhovac T, Cerić T, Mekić Abazović A, Alidžanović J, et al. Use of the depression, anxiety and stress scale (DASS-21) questionnaire to assess levels of depression, anxiety, and stress in healthcare and administrative staff in 5 oncology institutions in Bosnia and Herzegovina during the 2020 COVID-19 pandemic. Med Sci Monit 2021;27:e930812. https://doi.org/10.12659/MSM.930812

9. Alduraibi, R.K., Altowayan, W.M. A cross-sectional survey: knowledge, attitudes, and practices of self-medication in medical and pharmacy students. BMC Health Serv Res 2022;22:352. https://doi.org/10.1186/s12913-022-07704-0

10. Al-kubaisi KA, Abdulkarem A, Hassaneim M. Prevalence and associated risk factors of self-medication with over-the-counter medicines among university students in the United Arab Emirates. Pharm Pract 2022;20(3):01-06. https://doi.org/10.18549/pharmpract.2022.3.2679

11. Kanwal ZG, Fatima N, Azhar S, Chohan O, Jabeen M, Yameen MA. Implications of self-medication among medical students-a dilemma. J Pak Med Assoc 2018;68(9):1363-7.

12. Daanish AF, Mushkani EA. Influence of medical education on medicine use and self-medication among medical students: a cross-sectional study from Kabul. Drug Healthc Patient Saf 2022;14:79-85. https://doi.org/10.2147/DHPS.S360072

13. Araia ZZ, Gebregziabher NK, Mesfun AB. Self-medication practice and associated factors among students of Asmara College of Health Sciences, Eritrea: a cross sectional study. J Pharm Policy Pract 2019;12:3. https://doi.org/10.1186/s40545-019-0165-2

14. Kifle ZD, Mekuria AB, Anteneh DA, Enyew EF. Self-medication practice and associated factors among private health sciences students in Gondar Town, North West Ethiopia. A Cross-sectional Study. Inquiry 2021;58:469580211005188. https://doi.org/10.1177/00469580211005188

15. Kassie AD, Bifftu BB, Mekonnen HS. Self-medication practice and associated factors among adult household members in Meket district, Northeast Ethiopia, 2017. BMC Pharmacol Toxicol 2018;19(1):15. https://doi.org/10.1186/s40360-018-0205-6

16. Chuwa BB, Njau LA, Msigwa KI, Shao E. Prevalence and factors associated with self medication with antibiotics among University students in Moshi Kilimanjaro Tanzania. Afr Health Sci 2021;21(2):633-639. https://doi.org/10.4314/ahs.v21i2.19

17. Rashid M, Chhabra M, Kashyap A, Undela K, Gudi SK. Prevalence and predictors of self-medication practices in India: a systematic literature review and meta-analysis. Curr Clin Pharmacol 2020;15(2):90-101. https://doi.org/10.2174/1574884714666191122103953

18. Chopra D, Bhandari B, Sidhu JK, Jakhar K, Jamil F, Gupta R. Prevalence of self-reported anxiety and self-medication among upper and middle socioeconomic strata amidst COVID-19 pandemic. J Educ Health Promot 2021;10:73. https://doi.org/10.4103/jehp.jehp_864_20

19. Al Rasheed F, Naqvi AA, Ahmad R, Ahmad N. Academic stress and prevalence of stress-related self-medication among undergraduate female students of Health and Non-Health Cluster Colleges of a Public Sector University in Dammam, Saudi Arabia. J Pharm Bioallied Sci 2017;9(4):251-8. https://doi.org/10.4103/jpbs.JPBS_189_17

20. Gould LF, Hussong AM, Hersh MA. Emotional distress may increase risk for self-medication and lower risk for mood-related drinking consequences in adolescents. Int J Emot Educ 2012;4(1):6-24.

21. Habib SS, Al-Khlaiwi T, Almushawah A, Alsomali A, Bin Ateeq AAA, Aljarrah FA, et al. Prevalence and association of self-medication practices with personal and educational factors among university employees of Saudi Arabia: a cross-sectional study. J Family Med Prim Care 2024;13(11):5225-30. https://doi.org/10.4103/jfmpc.jfmpc_337_24

22. Alshahrani SM, Alavudeen SS, Alakhali KM, Al-Worafi YM, Bahamdan AK, Vigneshwaran E. Self-medication among King Khalid University Students, Saudi Arabia. Risk Manag Healthc Policy 2019;12:243-249. https://doi.org/10.2147/RMHP.S230257

23. Ibrahim NK, Alamoudi BM, Baamer WO, Al-Raddadi RM. Self-medication with analgesics among medical students and interns in King Abdulaziz University, Jeddah, Saudi Arabia. Pak J Med Sci 2015;31(1):14-8. https://doi.org/10.12669/pjms.311.6526

24. Elghazaly A, Alsahali S, Farooqui M, Ibrahim N, Alshammari M, Almutairi A, et al. A cross-sectional study to investigate the prevalence of self-medication of non-opioid analgesics among medical students at Qassim University, Saudi Arabia. Patient Prefer Adherence 2023;17:1371-9. https://doi.org/10.2147/PPA.S407693

25. Alhur A, Alhur A, Alfayiz A, Alotaibi A, Hansh B, Ghasib N, et al. Patterns and prevalence of self-medication in Saudi Arabia: insights from a nationwide survey. Cureus. 2023 Dec 29;15(12):e51281. https://doi.org/10.7759/cureus.51281

26. Okyay RA, Erdoğan A. Self-medication practices and rational drug use habits among university students: a cross-sectional study from Kahramanmaraş, Turkey. Peer J 2017;5:e3990. https://doi.org/10.7717/peerj.3990

27. Alomoush A, Alkhawaldeh A, ALBashtawy M, Hamaideh S, Ta'an W, Abdelkader R, et al. Self-medication and its associated factors among university students: a cross-sectional study. Iran J Nurs Midwifery Res 2024;29(2):268-71. https://doi.org/10.4103/ijnmr.ijnmr_302_22

Similar Articles

1 > >> 

You may also start an advanced similarity search for this article.

Most read articles by the same author(s)