THE BREAST MOUSE: AN OBSERVATIONAL STUDY OF BREAST FIBROADENOMAS IN THE PAKISTANI POPULATION

Main Article Content

Tarbia Hamid
Mah Muneer Khan
Ramsha Hamid

Abstract

OBJECTIVE: To assess the characteristics of fibroadenomas and demographics of women presenting with breast masses in order to differentiate such masses from malignant breast masses.


METHODS:  This cross-sectional survey was conducted at Khyber Teaching Hospital, Pakistan. Women with breast masses presenting to surgical outpatient department were assessed by taking a thorough history and breast examination, followed by imaging (ultrasound/mammography). Diagnosis was confirmed by fine needle aspiration cytology/Core biopsy. Only diagnosed cases of fibroadenomas were included in this study.


RESULTS: Majority (n=93; 70.5%) of fibroadenoma patients were aging from 16-30 years. Seventy (n=70; 53.0%) patients belonged to urban areas. Menstrual cycle was regular in 123 (93.2%) cases. Sixty-four (48.5%) patients were using oral contraceptive pills. Majority (n=79; 59.8%) of patients were nulliparous.  Most (38.6%) women presented with a duration of the lump in 1-6 months. Approximately half (n=51; 53 %) of patient reported no increase in size. Lump was painful in 77 (58.3%) cases and 34 (74.2%) stated that the pain was acyclical. Lumps were mainly located on left side (n=64; 48.5%) and in upper outer quadrants (n=54; 40.9%) of breast. Mean lump size was 4.05 cm. Only 9 (6.8%) patients reported nipple discharge. Almost all of the patients (n=128; 97%) chose to undergo excision of the fibroadenoma.


CONCLUSION: Fibroadenomas are a common presentation in women presenting with breast masses in the surgical outpatient department, most frequent in women aging 16-30 years and nulliparous. There is a strong predominance in the left breast in the upper outer quadrant.

Article Details

How to Cite
Hamid, Tarbia, et al. “THE BREAST MOUSE: AN OBSERVATIONAL STUDY OF BREAST FIBROADENOMAS IN THE PAKISTANI POPULATION”. KHYBER MEDICAL UNIVERSITY JOURNAL, vol. 14, no. 3, Sept. 2022, pp. 173-8, doi:10.35845/kmuj.2022.21668.
Section
Original Articles

References

Bharati Pandya, Wahane SM, Narang R. Clinical profile of fibroadenoma in rural Vidharbha: A Geographical Entity in Central India. Int J Recent Sci Res 2015;6(7):5117-20.

Vijaykumar A, Ajitha MB, Shivaswamy BS, Srinivasan N. A Systematic Study on Fibroadenoma of the Breast. Int J Biomed Adv Res 2012;3(12):891-5. https://doi.org/10.7439/ijbar.v3i12.826

Rangabashyam N, Gnanaprakasan D, Krishnaraj B, Manohar V, Vijayalakshmi SR. Spectrum of benign breast lesions in Madras. J R Coll Surg Edinb 1983;28(6):369-73.

Deschenes L, Jacob S, Fabia J, Christen A. Beware of breast fibroadenoma in middle- aged women. Can J Surg 1985;28(4):372-4.

Tiryaki T, Senel E, Hucumenoglu S, Cakir BC, Kibar AE. Breast fibroadenoma in female adolescents. Saudi Med J 2007;28(1):137-8.

Alagar SR, Purushothaman R. An analytical study on fibroadenoma of the breast: ESIC medical college and hospital, Coimbatore, Tamilnadu, India. CIBTech J Surg 2015;4(2):40-5.

Kalim M, Ahmad S, Shah FO, Yosaf M. Frequency of fibroadenoma in patients presenting with breast lump. J Postgrad Med Inst 2018;32(1): 95-8.

Rashid R, Haq SM, Khan K, Jamal S, Khaliq T, Shah A. Benign breast disorders, a clinicopathological study. Ann Pak Inst Med Sci 2005;1(4):187-90.

Memon SS, ValiRam P, Memon MS. Clinico-pathological profile of breast lesions at a tertiary care centre in Karachi, Pakistan. Pak J Surg 2020;36(1):25-8.

Franyz VK, Pickern JW, Melcher GW, Auchincoloss Jr. Incidence of chronic cystic disease in so-called normal breast: a study based on 225 postmortem examinations. Cancer 1951;4(4):762-83. https://doi.org/10.1002/1097-0142(195107)4:4%3C762::aid-cncr2820040414%3E3.0.co;2-v

Hanna RM, Ashebu SD. Giant fibroadenoma of the breast in an Arab population. Australas Radiol 2002;46(3):252-6. https://doi.org/10.1046/j.1440-1673.2002.01054.x

Gogo-Abite M, Seleye-Fubara D, Jamabo RS. Fibroadenoma coexisting with infiltrating ductal carcinoma-- a case report. Niger J Med 2005;14(2):221-3. https://doi.org/10.4314/njm.v14i2.37185

Yu H, Rohan TE, Cook MG, Howe GR, Miller AB. Risk factor for fibroadenoma: a case control study in Australia. Am J Epidemiol 1992;135(3):247-58. https://doi.org/10.1093/oxfordjournals.aje.a116278

Canny PF, Berkowitz GS, Kelsey JL, LiVolsi VA. Fibroadenoma and the use of exogenous hormones: a case control study. Am J Epidemiol 1988;127(3):454-61. https://doi.org/10.1093/oxfordjournals.aje.a114822

Rimsten A. Symptoms and signs in benign and malignant tumors of the breast. Upps J Med Sci 1976;81(1):54-60. https://doi.org/10.3109/03009737609179022

Alamri AM, Alsareii SA, Al-Wadei H, Al-Qahtani AM, Sultan SA, et al. Epidemiological pattern of breast diseases among females in the south-western region, Saudi Arabia. Int J Clin Med 2020 May 15;11(05):257.

Ajao OG. Benign breast lesions. J Natl Med Assoc 1979;71(9):867-8.

Zeeshan S, Shaikh K, Tariq MU, Vohra LM. Giant Juvenile Fibroadenoma of the breast in a 13-year-old Pakistani girl with excellent cosmetic outcome after subareolar enucleation–A case report. J Surg Case Rep 2021;79:450-4. https://doi.org/10.1016/j.ijscr.2021.01.094

Pike AM, Oberman HA. Juvenile cellular adenofibromas. Am J Surg Pathol 1985;9(10):730-6. https://doi.org/10.1097/00000478-198510000-00004

Wilkinson S, Anderson TJ, Rifkind E, Chetty U, Forrest AP. Fibroadenoma of the breast: a follow-up of conservative management. Br J Surg 1989;76(4):390-1. https://doi.org/10.1002/bjs.1800760424

Ranieri E, Barberi S, Caprio G, Civitelli L, Naticchioni E, Ceccarelli F, et al. Diagnosis and treatment of Fibroadenoma of the breast: 20 years’ experience. Chir Ital 2006;58(3):295-7.

Greenblatt RB, Nezhat C, Ben-Nun I. The treatment of benign breast disease with danazol. Fertil Steril 1980;34(3):242-5.

Liu XF, Zhang JX, Zhou Q, Chen F, Shao ZM, Lu C. A clinical study on the resection of breast Fibroadenoma using two types of incision. Scand J Surg 2011;100(3):147-52. https://doi.org/10.1177/145749691110000302

Schuerch 3rd C, Rosen PP, Hirota T, Itabashi M, Yamamoto H, Kinne DW, et al. A pathologic study of benign breast disease in Tokyo and New York. Cancer 1982;50(9):1899-902. https://doi.org/10.1002/1097-0142(19821101)50:9%3C1899::aid-cncr2820500942%3E3.0.co;2-a

Ahmed HG, Ali AS, Almobarak AO. Frequency of breast cancer among Sudanese patients with breast palpable lumps. Indian J Cancer 2010;47(1):23-6. https://doi.org/10.4103/0019-509x.58854

Gordon PB, Gagnon FA, Lanzkowsky L. Solid breast masses diagnosed as fibroadenoma at fine-needle aspiration biopsy: acceptable rates of growth at long-term follow-up. Radiology 2003;229(1):233-8. https://doi.org/10.1148/radiol.2291010282

Alle KM, Moss J, Venegas RJ, Khalkhali I, Klein SR. Conservative management of fibroadenoma of the breast. Br J Surg 1996;83(7):992–3. https://doi.org/10.1002/bjs.1800830735

Cant PJ, Madden MV, Close PM, Learmonth GM, Hacking EA, Dent DM. Case for conservative management of selected Fibroadenoma of the breast. Br J Surg 1987;74(9):857-9. https://doi.org/10.1002/bjs.1800740936

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