USING HEALTH INSURANCE DATABASES FOR EPIDEMIOLOGICAL RESEARCH: A SCOPING REVIEW

Main Article Content

Sheraz Ahmad Khan
https://orcid.org/0000-0001-6679-9052
Raheel Shahab Khan
Ayisha Jamil

Abstract

OBJECTIVE: This scoping review aimed to appraise the existing literature on using the claims databases for epidemiological studies and to draw inferences for using data from Pakistan’s health insurance databases.


METHODS: We conducted a scoping review of literature focusing on health insurance databases, querying MEDLINE, EMBASE and Google Scholar. We used the frameworks proposed by the Joanna Briggs Institute and Arksy and O’Malley for mapping our results.


RESULTS:  There was a considerable chronological increase in studies published using data from health insurance databases. Most of the studies in our search were from economically developed countries. Most of the studies (n=84) focussed on chronic non-communicable diseases, while a limited number (n=09) focussed on communicable (infectious) diseases. Our findings suggest that insurance databases could be utilised to study rare diseases, prospects of prolonged follow-up, and minimal research costs. This is especially important for countries like Pakistan, having limited resources to conduct regular, population-level epidemiological studies. Several methodological approaches (for instance, disease, pharmacy or intervention classification codes) were presented in these studies to extract epidemiological data from the insurance database.


CONCLUSION: Health insurance databases are utilised as sources for epidemiological studies, predominantly for chronic illnesses, in economically developed countries. Methodological approaches described in these papers could be used to extract data for epidemiological research from health insurance databases in Pakistan. This could be especially useful for following the patterns of infectious disease in the country.

Article Details

How to Cite
Khan, S. A., R. S. Khan, and A. Jamil. “USING HEALTH INSURANCE DATABASES FOR EPIDEMIOLOGICAL RESEARCH: A SCOPING REVIEW”. KHYBER MEDICAL UNIVERSITY JOURNAL, vol. 14, no. 4, Dec. 2022, pp. 281-91, doi:10.35845/kmuj.2022.21480.
Section
Narrative Review Articles

References

Nishtar S, Boerma T, Amjad S, Alam AY, Khalid F, Ul Haq I, et al. Pakistan’s health system: Performance and prospects after the 18th Constitutional Amendment. Lancet 2013;381(9884):2193-206. https://doi.org/10.1016/s0140-6736(13)60019-7

Nishtar S, Bhutta ZA, Jafar TH, Ghaffar A, Akhtar T, Bengali K, et al. Health reform in Pakistan: A call to action. Lancet 2013;381(9885):2291-7. https://doi.org/10.1016/s0140-6736(13)60813-2

World Health Organization. Pakistan: Health information system [Internet]. 2019 [Accssed on: September 29, 2020]. Available from URL: http://www.emro.who.int/pak/programmes/health-managment-information-system.html

JSI Research & Training Institute I (JSI). Strong Systems Save Lives. Health Systems Strengthening Component of USAID’s Maternal and Child Health Program. Boston, MA; 2017. [Accessed on: September 20, 2020]. Available from URL: https://publications.jsi.com/JSIInternet/Inc/Common/_download_pub.cfm?id=18712&lid=3

World Health Organization. Monitoring the building blocks of health systems : a handbook of indicators and [Internet]. Geneva, Switzerland; 2010. [Accssed on: September 29, 2020]. Available from URL: https://www.who.int/healthinfo/systems/WHO_MBHSS_2010_full_web.pdf

Khan SA. Pakistan’s march towards universal health coverage. J Ayub Med Coll Abbottabad 2017;29(4):533-4.

Khan SA. Comparison of Federal and Khyber Pakhtunkhwa health insurance Schemes; Qualitative analysis of their proximity to Universal Health Coverage. Khyber Medical University; 2016. Accssed on: September 29, 2020]. Available from URL: https://www.academia.edu/34887526/Comparison_of_Federal_and_Khyber_Pakhtunkhwa_health_insurance_Schemes_Qualitative_analysis_of_their_proximity_to_Universal_Health_Coverage

Angell BJ, Prinja S, Gupt A, Jha V, Jan S. The Ayushman Bharat Pradhan Mantri Jan Arogya Yojana and the path to universal health coverage in India: Overcoming the challenges of stewardship and governance. PLoS Med 2019;16(3):e1002759. https://doi.org/10.1371/journal.pmed.1002759

Querri A, Ohkado A, Kawatsu L, Remonte MA, Medina A, Garfin AMC. The challenges of the Philippines’ social health insurance programme in the era of universal health coverage. Public Heal action. 2018;8(4):175-80. https://doi.org/10.5588%2Fpha.18.0046

Khan SA, Shahab R, Khattak AR. First-Year Report on services’ utilisation under the universal population coverage conferred by the social health protection initiative (Sehat Card Plus) in Khyber Pakhtunkhwa, Pakistan. Peshawar; 2022.

Nawaz R, Khan SA, Khan GS. SWOT analysis of district health information system in khyber pakhtunkhwa. Gomal J Med Sci 2015;13(2);109-14.

Karuri J, Waiganjo P, Orwa D, Manya A, Daniel O, Manya A. DHIS2: the tool to improve health data demand and use in Kenya. J Heal Inf Dev Countr 2014;8(1):38-60.

Shin S. A Case Study On The National Database Project In Korea. In: Electronic Government and Electronic Participation: Joint Proceedings of Ongoing Research and Projects of IFIP WG 85 EGOV and ePart 2012. 2012.

Harbaugh CM, Cooper JN. Administrative databases. Semin Pediatr Surg 2018;27(6):353-360. https://doi.org/10.1053/j.sempedsurg.2018.10.001

Chen YC, Yeh HY, Wu JC, Haschler I, Chen TJ, Wetter T. Taiwan’s National Health Insurance Research Database: Administrative health care database as study object in bibliometrics. Scientometrics 2011;86:365-80. https://doi.org/10.1007/s11192-010-0289-2

Piecoro LT, Wang LS, Dixon WS, Crovo RJ. Creating a computerised database from administrative claims data. Am J Heal Syst Pharm 1999;56(13):1326-9. https://doi.org/10.1093/ajhp/56.13.1326

Ferdynus C, Huiart L. Technical improvement of cohort constitution in administrative health databases: Providing a tool for integration and standardisation of data applicable in the French National Health Insurance Database (SNIIRAM). Rev Epidemiol Sante Publique 2016;64(4):263-9. https://doi.org/10.1016/j.respe.2016.02.011

Kwon YW, Lee SH, Kim HW, Hwang JH. The Pattern of Occurrence of Fractures in Children and Adolescents and Its Managements Based on the Database of the Health Insurance Review and Assessment Service. J Korean Fract Soc 2014;27(4):308-14. http://dx.doi.org/10.12671/jkfs.2014.27.4.308

Lee CH, Sung NY. The prevalence and features of Korean gout patients using the National Health Insurance Corporation database. J Rheum Dis 2011;18(2):94-100. http://dx.doi.org/10.4078/jrd.2011.18.2.94

Park SY, Kim JE, Lee JY, Lim NG, Hong YH. Incidence and prevalence of myasthenia gravis in Korea: A population-based study using the national health insurance claims database. J Clin Neurol 2016;12(3):340-4. https://doi.org/10.3988/jcn.2016.12.3.340

Lim JS, Kwon HM, Kim SE, Lee YS, Yoon BW. Effects of temperature and pressure on acute stroke incidence assessed using a korean nationwide insurance database. J Stroke 2017;19(3):295-303. https://doi.org/10.5853/jos.2017.00045

Shin WY, Lee T, Jeon D-HH, Kim HC. Diabetes, frequency of exercise, and mortality over 12 years: Analysis of the National Health Insurance Service-Health Screening (NHIS-HEALS) Database. J Korean Med Sci 2018;33(8):e60. https://doi.org/10.3346/jkms.2018.33.e60

Koo BK, Lee CH, Yang BR, Hwang SS, Choi NK. The incidence and prevalence of diabetes mellitus and related atherosclerotic complications in Korea: A National Health Insurance database study. PLoS One 2014;9(10):e110650. https://doi.org/10.1371/journal.pone.0110650

Lee SE, Han K, Kang YM, Kim SO, Cho YK, Ko KS, et al. Trends in the prevalence of metabolic syndrome and its components in South Korea: Findings from the Korean National Health Insurance Service Database (2009-2013). PLoS One 2018;13 (3):e0194490. https://doi.org/10.1371/journal.pone.0194490

Chun BC, Noh HO. Changes of invasive pneumococcal disease burden in Korea, 2005- 2014: Analysis of the national health insurance database. Open Forum Infect Dis Conf 2016;3(Supplement 1):1433. https://doi.org/10.1093/ofid/ofw172.1136

Lim DH, Kim YJ, Kim SO, Hong S, Lee CK, Yoo B, et al. The risk of herpes zoster in patients with ankylosing spondylitis: Analysis of the Korean National Health Insurance Service-Sample cohort database. Mod Rheumatol [Internet]. 2018;28(1):168-73. https://doi.org/10.1080/14397595.2017.1325034

Kang EJ, Seo JH, Kim LY, Park GU, Oh MJ, Park PJ, et al. Pregnancy-Associated risk factors of postpartum breast cancer in korea: A nationwide health insurance database study. PLoS One 2016;11(12):e0168469. https://doi.org/10.1371/journal.pone.0168469

Choi CM, Park S, Lee HN, Oh DK, Ji WJ, Kim S, et al. Chest radiography surveillance for lung cancer: Results from a National Health Insurance database in South Korea. Lung Cancer 2019;128:120-6. https://doi.org/10.1016/j.lungcan.2018.12.024

Kang S, Kim HS, Choi ES, Han I. Incidence and treatment pattern of extremity soft tissue sarcoma in Korea, 2009-2011: A nationwide study based on the health insurance review and assessment service database. Cancer Res Treat 2015;47(4):575-82. https://doi.org/10.4143/crt.2014.047

Choi HJ, Shin CS, Ha YC, Jang SM, Jang SH, Park CM, et al. Burden of osteoporosis in adults in Korea: a national health insurance database study. J Bone Miner Metab 2012;30(1):54-8. https://doi.org/10.1007/s00774-011-0280-x

Shin H-R, Won Y-J, Jung K-W, Kong H-J, Yim S-H, Lee J-KJ-K, et al. Nationwide cancer incidence in Korea, 1999~ 2001; first result using the national cancer incidence database. Cancer Res Treat 2005;37(6):325-31. https://doi.org/10.4143/crt.2005.37.6.325

Chung C, Jang C, Myung W, Kang D, Park H, Cho J, et al. The epidemiology of psychiatric illness in survivors of critical illness in Korea-a national health insurance database study, 2009-2014. Am J Respir Crit Care Med 2017;195.

Park H, Song I, Shin JY. High Prevalence of Depression Diagnosis Among Medical Aid Beneficiaries: A Korean Health Insurance Database Study. Asia Pacific J Public Health 2017;29(8):692-7. https://doi.org/10.1177/1010539517745807

Yang MS, Lee JY, Kim J, Kim GW, Kim BK, Kim JY, et al. Incidence of stevens-johnson syndrome and toxic epidermal necrolysis: A nationwide population-based study using national health insurance database in Korea. PLoS One 2016;11(11):e0165933. https://doi.org/10.1371/journal.pone.0165933

Yoon HK, Chang JS, Kim DY, Ha YC, Choi HJ, Jang SM. Osteoporosis prevalence among adults in Korea: National Health Insurance database study. Osteoporos Int [Internet]. 2010;5):S720-1.

Hong J-S, Kang H-CC. Seasonal variation in case fatality rate in Korean patients with acute myocardial infarction using the 1997-2006 Korean National Health Insurance Claims Database. Acta Cardiol 2014;69(5):513-21. https://doi.org/10.1080/ac.69.5.3044878

Son MK, Lim N-K, Cho M-C, Park H-Y. Incidence and risk factors for atrial fibrillation in Korea: the National Health Insurance Service Database (2002–2010). Korean Circ J 2016;46(4):515-21. https://doi.org/10.4070/kcj.2016.46.4.515

Chon MK, Kim JHS, Lee SHY, Hwang JM, Lee SHY, Hwang KW, et al. Prevalence, recognition and treatment of atherosclerotic cardiovascular disease in Korea: From 2002 to 2010 Korea health insurance sample cohort database (KHISCDB). Eur Heart J 2015;36(1):849-1187 (P6463). https://doi.org/10.1093/eurheartj/ehv401

Song S, Lee SE, Oh SK, Jeon SA, Sung JM, Park JH, et al. Demographics, treatment trends, and survival rate in incident pulmonary artery hypertension in Korea: A nationwide study based on the health insurance review and assessment service database. PLoS One 2018;13 (12):e0209148. https://doi.org/10.1371/journal.pone.0209148

Jang MJ, Bang SM, Oh D. Incidence of pregnancy-associated venous thromboembolism in Korea: from the Health Insurance Review and Assessment Service database. J Thromb Haemost 2011;9(12):2519-21. https://doi.org/10.1111/j.1538-7836.2011.04518.x

Jang MJ, Bang S, Oh D. Incidence of venous thromboembolism in Korea: From the Health Insurance Review and Assessment Service database. J Thromb Haemost 2011;9(1):85-91. https://doi.org/10.1111/j.1538-7836.2010.04108.x

Islam S, Liu Q, Chines A, Helzner E. Trend in incidence of osteoporosis-related fractures among 40- to 69-year-old women: Analysis of a large insurance claims database, 2000-2005. Menopause 2009;16(1):77-83. https://doi.org/10.1097/gme.0b013e31817b816e

Lin TTL, Juang JJJ, Wu CKWCW, Liao MTL, Wu CKWCW, Lin LYL. Atrial fibrillation and the risk of sudden cardiac death in patients with hypertrophic cardiomyopathy-a nationwide cohort study using insurance claims database. Eur Heart J 2018;39 (Suppl 1): ehy564.P1015. https://doi.org/10.1093/eurheartj/ehy564.P1015

Insinga RP, Itzler RF, Pellissier JM, Saddier P, Nikas AA. The incidence of herpes zoster in a United States administrative database. J Gen Intern Med 2005;20(8):748-53. https://doi.org/10.1111/j.1525-1497.2005.0150.x

Loughlin J, Poulios N, Napalkov P, Wegmüller Y, Monto AS. A study of influenza and influenza-related complications among children in a large US health insurance plan database. Pharmacoeconomics 2003;21(4):273-83. https://doi.org/10.2165/00019053-200321040-00005

Williams J, Kerr D, Farwell W. Incidence of Serious Infections among Patients with ALS in a US Health Insurance Claims Database (P07.086). Neurology 2013:80(07);P07.086.

Broder MS, Cai B, Chang E, Neary MP. Incidence and prevalence of neuroendocrine tumors of the lung: Analysis of a US commercial insurance claims database. BMC Pulm Med 2018;18(1):135. https://doi.org/10.1186/s12890-018-0678-5

Fedewa SA, Etzioni R, Flanders WD, Jemal A, Ward EM. Association of insurance and race/ethnicity with disease severity among men diagnosed with prostate cancer, National Cancer Database 2004-2006. Cancer Epidemiol Biomarkers Prev 2010;19(10):2437-44. https://doi.org/10.1158/1055-9965.epi-10-0299

Matusiewicz D, Koerber A, Schadendorf D, Wasem J, Neumann A. Childhood psoriasis—an analysis of German health insurance data. Pediatr Dermatol 2014;31(1):8-13. https://doi.org/10.1111/pde.12205

Park S, Lee S, Jo HA, Han K, Kim YS, An JN, et al. Epidemiology of continuous renal replacement therapy in Korea: Results from the national health insurance service claims database from 2005 to 2016. Kidney Res Clin Pract 2018;37(2):119-29. https://doi.org/10.23876/j.krcp.2018.37.2.119

Dubreuil M, Peloquin C, Felson DT, Neogi T. Myocardial infarctions among ankylosing spondylitis patients in a large U.S insurance database. Arthritis Rheumatol 2018;70 (Suppl 9):1786-7. Available from URL: https://acrabstracts.org/abstract/myocardial-infarctions-among-ankylosing-spondylitis-patients-in-a-large-us-insurance-database/

Mues KE, Philip K, Bradbury BD, Schneeweiss SS, Monda KL. Cardiovascular event rates among patients with peripheral arterial disease in a United States administrative insurance claims database. Circulation 2018;138(Suppl 1):A16712.

Kupelian V, Viscidi E, Hall S, Li L, Eaton S, Dilley A, et al. Incidence of Venous Thromboembolic Events Among Amyotrophic Lateral Sclerosis Patients in a US Health Insurance Claims Database (P4.6-003) Neurology 2019;92(Suppl 15):P4.6-003.

Williams JR, Kerr D, Farwell W. Incidence of neutropenia among hospitalised AL patients in a US Health insurance claims database. Amyotroph Lateral Scler. 2012;1):126–7.

Williams JR, Kerr DA, Farwell W. Prevalence of medical comorbidity among ALS patients in a U.S. health insurance claims database. Eur J Neurol 2012;19(Suppl 1):271.

Corwin M, Reshef S, Golub H, Cutter G, Kaufman D, Pleimes D, et al. Subcategory Analysis of Causes of Death in Patients with Multiple Sclerosis from a Large US Insurance Database (S30.007). Neurol 2013;80(Suppl 7):S30.007.

Vinikoor-Imler LC, Li L, Eaton S, Dilley A. Patient profile of trigeminal neuralgia: A US insurance claims database study. Pharmacoepidemiol Drug Saf 2017;26(Suppl 2):284 (A 469). https://doi.org/10.1002/pds.4274

O’Connor PJ, Rush WA, Pronk NP, Cherney LM. Identifying diabetes mellitus or heart disease among health maintenance organisation members: sensitivity, specificity, predictive value, and cost of survey and database methods. Am J Manag Care 1998;4(3):335–42.

Chie WC, Yang RS, Liu JP, Tsai KS. High incidence rate of hip fracture in Taiwan: estimated from a nationwide health insurance database. Osteoporos Int [Internet]. 2004;15(12):998-1002. https://doi.org/10.1007/s00198-004-1651-0

Yang N-PP, Deng C-YY, Chou Y-JJ, Chen P-QQ, Lin C-HH, Chou P, et al. Estimated prevalence of osteoporosis from a Nationwide Health Insurance database in Taiwan. Health Policy 2006;75(3):329-37. https://doi.org/10.1016/j.healthpol.2005.04.009

Tseng CH. Diabetes and risk of bladder cancer: A study using the National Health Insurance database in Taiwan. Diabetologia 2011;54(8):2009-15. https://doi.org/10.1007/s00125-011-2171-z

Chen YC, Lin CH, Chang SN, Shi ZY. Epidemiology and clinical outcome of pyogenic liver abscess: an analysis from the National Health Insurance Research Database of Taiwan, 2000-2011. J Microbiol Immunol Infect 2016;49(5):646-53. https://doi.org/10.1016/j.jmii.2014.08.028

Chiang J-K, Lin C-W, Wang C-L, Koo M, Kao Y-H. Cancer studies based on secondary data analysis of the Taiwan’s National Health Insurance Research Database: A computational text analysis and visualisation study. Medicine (Baltimore) 2017;96(17)e6704. https://doi.org/10.1097/md.0000000000006704

Lian IB, Tseng YT, Su CC, Tsai KY. Progression of precancerous lesions to oral cancer: Results based on the Taiwan National Health Insurance Database. Oral Oncol 2013;49(5):427-30. https://doi.org/10.1016/j.oraloncology.2012.12.004

Tai YM, Chiu HW. Comorbidity study of ADHD: Applying association rule mining (ARM) to National Health Insurance Database of Taiwan. Int J Med Inform 2009;78(12):e75-83. https://doi.org/10.1016/j.ijmedinf.2009.09.005

Hung YN, Kadziola Z, Brnabic AJM, Yeh JF, Fuh JL, Hwang JP, et al. The epidemiology and burden of Alzheimer’s disease in Taiwan utilising data from the National Health Insurance Research Database. Clinicoecon Outcomes Res 2016;8:387–95. https://doi.org/10.2147/ceor.s93323

Chang Y-TT, Chen T-JJ, Liu P-CC, Chen Y-CY-JJC, Chen Y-CY-JJC, Huang Y-LL, et al. Epidemiological study of psoriasis in the national health insurance database in Taiwan. Acta Derm Venereol 2009;89(3):262-6. https://doi.org/10.2340/00015555-0642

Chang C, Yeh G, Lee Y, Chen T, Tseng I, Lin S, et al. Hemophilia in Taiwan: A population-based study on epidemiology, age at diagnosis, mortality, and 13-year trend by national health insurance research database 1997-2009. Haemophilia 2014;20(4):535-40. https://doi.org/10.1111/hae.12373

Grosse SD, Boulet SL, Grant AM, Hulihan MM, Faughnan ME. The use of US health insurance data for surveillance of rare disorders: hereditary hemorrhagic telangiectasia. Genet Med 2014;16(1):33-9. https://doi.org/10.1038/gim.2013.66

Hsieh CY, Cheng CL, Lai ECC, Wang MC, Chen CH, Li CY, et al. Identifying renal dysfunction in stroke patients using diagnostic codes in the Taiwan National Health Insurance Research Database. Int J Stroke 2015;10(1):E5. https://doi.org/10.1111/ijs.12380

Kang JH, Lin HC. Association between osteoporosis and psoriasis: Results from the Longitudinal Health Insurance Database in Taiwan. Osteoporos Int 2013;24(6):1835-41. https://doi.org/10.1007/s00198-012-2185-5

Te ALD, Wu TC, Lin YJ, Chen YY, Chung FP, Chang SL, et al. Increased risk of ventricular tachycardia and cardiovascular death in patients with myocarditis during the long-term follow-up: A national representative cohort from the National Health Insurance Research Database. Medicine (Baltimore) 2017;96(18):e6633. https://doi.org/10.1097/md.0000000000006633

Chang CL, Wong CS, Yang YC, Chiu NC. Influence of latitude on the prevalence of Kawasaki disease: A retrospective cohort study from the Taiwan national health insurance database and review of the literature. Int J Environ Res Public Health 2018;15(5):845. https://doi.org/10.3390/ijerph15050845

Chien I-C, Lin Y-C, Chou Y-J, Lin C-H, Bih S-H, Lee C-H, et al. Treated prevalence and incidence of dementia among National Health Insurance enrollees in Taiwan, 1996-2003. J Geriatr Psychiatry Neurol 2008;21(2):142-8. https://doi.org/10.1177/0891988708316859

Lee WW, Jeon B, Kim HJ, Lee J, Kim A, Jang MH. A nationwide epidemiologic study of Parkinson’s disease in Korea using national health insurance database. Park Relat Disord 2018;46(Suppl 2):e75. https://doi.org/10.1016/j.parkreldis.2017.11.258

Chang CH, Shau WY, Jiang YD, Li HY, Chang TJ, Sheu WHH, et al. Increasing disease burden of type 2 diabetes mellitus among chinese in Taiwan: An analysis of the database of national health insurance claims in 1999-2004. Am Diabetes Assoc 2009 (69th Scientific Sessions);Abstract 998-P.

Tseng CH. Diabetes and non-Hodgkin’s lymphoma: Analyses of prevalence and annual incidence in 2005 using the national health insurance database in Taiwan. Ann Oncol 2012;23(1):153-8. https://doi.org/10.1093/annonc/mdr334

Koo BK, Lee JH, Kim J, Jang EJ, Lee CH. Prevalence of gestational diabetes mellitus in Korea: A National Health Insurance Database Study. PLoS One 2016;11(4):e0153107. https://doi.org/10.1371/journal.pone.0153107

Iihara N, Ohara E, Bando Y, Yoshida T, Ohara M, Kirino Y. Fragility fractures in older people in Japan based on the National Health Insurance Claims database. Biol Pharm Bull 2019;42(5):778-85. https://doi.org/10.1248/bpb.b18-00974

Hayashi S, Noda T, Kubo S, Myojin T, Nishioka Y, Higashino T, et al. Data regarding fracture incidence according to fracture site, month, and age group obtained from the large public health insurance claim database in Japan. Data Brief 2019;23:103780. https://doi.org/10.1016/j.dib.2019.103780

Hayashi S, Noda T, Kubo S, Myojin T, Nishioka Y, Higashino T, et al. Variation in fracture risk by season and weather: A comprehensive analysis across age and fracture site using a National Database of Health Insurance Claims in Japan. Bone 2019;120:512-8. https://doi.org/10.1016/j.bone.2018.12.014

Sakai R, Hirano F, Kihara M, Yokoyama W, Yamazaki H, Koike R, et al. FRI0088 Prevalence of comorbidities in patients with rheumatoid arthritis using Japanese health insurance database. Ann Rheum Dis 2014;73(Suppl 2):413. http://dx.doi.org/10.1136/annrheumdis-2014-eular.1296

Kasai S, Hirano F, Kihara M, Yokoyama W, Tsutsumino M, Nagasaka K, et al. Incidence rate and the risk of herpes zoster in patients with rheumatoid arthritis using Japanese health insurance database. Ann Rheum Dis 2016;75(Suppl 2):481. http://dx.doi.org/10.1136/annrheumdis-2016-eular.2414

Morimoto K, Izumi K, Uchimura K, Hasegawa N, Namkoong H, Hoshino Y, et al. Prevalence of nontuberculous mycobacterial pulmonary disease in Japan: Analysis of national database of medical insurance claim. Am J Respir Crit Care Med (Abstracts of Conf Am Thorac Soc Int Conf) 2017;195(no pagination).

Heyer K, Herberger K, Protz K, Glaeske G, Augustin M. Epidemiology of chronic wounds in Germany: Analysis of statutory health insurance data. Wound Repair Regen 2016;24(2):434-42. https://doi.org/10.1111/wrr.12387

Augustin M, Reich K, Glaeske G, Schaefer I, Radtke M. Co-morbidity and age-related prevalence of psoriasis: analysis of health insurance data in Germany. Acta Derm Venereol 2010;90(2):147-51. https://doi.org/10.2340/00015555-0770

Breban M, Claudepierre P, De Chalus T, Joubert JM, Laurendeau C, Gourmelen J, et al. Prevalence determination of severe ankylosing spondylitis and its co-morbidities in 2012 in France: Analysis of a national public health insurance database. Ann Rheum Dis 2015;74:505-6. http://dx.doi.org/10.1136/annrheumdis-2015-eular.2039

Claudepierre P, Breban M, De Chalus T, Joubert J, Laurendeau C, Gourmelen J, et al. Prevalence, comorbidities and burden of severe spondyloarthritis in France: Analysis of a national public health insurance database in 2012 in France. Value Heal 2015;18(7):PA637. https://doi.org/10.1016/j.jval.2015.09.2267

Vorilhon C, Chouki C, Mulliez A, Eschalier A, Motreff P, Lusson JR, et al. Heart failure epidemiology management and prognosis in over 80 years old patients: A cohort study in the French national healthcare insurance database. Eur Heart J 2014;35(Suppl 1):513-850(P3673). https://doi.org/10.1093/eurheartj/ehu324

Bertrand M, Tzourio C, Alperovitch A. Trends in recognition and treatment of dementia in france analysis of the 2004 to 2010 database of the national health insurance plan. Alzheimer Dis Assoc Disord 2013;27(3):213-7. https://doi.org/10.1097/wad.0b013e3182695a3b

Kab S, Moisan F, Preux PM, Marin B, Elbaz A. Nationwide incidence of motor neuron disease using the French health insurance information system database. Amyotroph Lateral Scler Frontotemporal Degener 2017;18(5-6):426-33. https://doi.org/10.1080/21678421.2017.1306566

Foulon S, Maura G, Dalichampt M, Alla F, Debouverie M, Moreau T, et al. Prevalence and mortality of patients with multiple sclerosis in France in 2012: a study based on French health insurance data. J Neurol 2017;264(6):1185-92. https://doi.org/10.1007%2Fs00415-017-8513-0

Blin P, Dureau-Pournin C, Foubert-Samier A, Grolleau A, Corbillon E, Jove J, et al. Parkinson’s disease incidence and prevalence assessment in France using the national healthcare insurance database. Eur J Neurol 2015;22(3):464-71. https://doi.org/10.1111/ene.12592

Barbut F, Bouee S, Longepierre L, Goldberg M, Bensoussan C, Levy-Bachelot L. Excess mortality between 2007 and 2014 among patients with Clostridium difficile infection: a French health insurance database analysis. J Hosp Infect 2018;98(1):21-8. https://doi.org/10.1016/j.jhin.2017.07.006

Vinet E, Kuriya B, Widdifield J, Bernatsky S. Rheumatoid arthritis disease severity indices in administrative databases: a systematic review. J Rheumatol 2011;38(11):2318-25. https://doi.org/10.3899/jrheum.110587

Young TK, Roos NP, Hammerstrand KM. Estimated burden of diabetes mellitus in Manitoba according to health insurance claims: a pilot study. Can Med Assoc J 1991;144(3):318.

Ribeiro M, Fritz L, Vernich L, Liss G, Tarlo S. Trends in the outcomes of irritant-induced work-related asthma from a workers compensation and insurance agency database in Canada. Chest 2017;152(4):A828. https://doi.org/10.1016/j.chest.2017.08.860

Meyer G, Neumann K, Badenhoop K, Linder R. Increasing prevalence of Addison’s disease in German females: health insurance data 2008-2012. Eur J Endocrinol 2014;170(3):367-73. https://doi.org/10.1530/eje-13-0756

Meyer G, Badenhoop K, Linder R. Addison’s disease with polyglandular autoimmunity carries a more than 2· 5‐fold risk for adrenal crises: German Health insurance data 2010-2013. Clin Endocrinol (Oxf) 2016;85(3):347-53. https://doi.org/10.1111/cen.13043

Hoffmann F, Glaeske G, Petermann F, Bachmann CJ. Outpatient treatment in German adolescents with depression: an analysis of nationwide health insurance data. Pharmacoepidemiol Drug Saf 2012;21(9):972-9. https://doi.org/10.1002/pds.3295

Pentek M, Horvath C, Boncz I, Falusi Z, Toth E, Sebestyen A, et al. Epidemiology of osteoporosis related fractures in Hungary from the nationwide health insurance database, 1999-2003. Osteoporos Int 2008;19(2):243-9. https://doi.org/10.1007/s00198-007-0453-6

Kurti Z, Gonczi L, Golovics PA, Lovasz BD, Vegh Z, Lakatos PL. Nationwide prevalence of inflammatory bowel diseases in Hungary. A population-based study based on the national health insurance fund database. Gastroenterology 2016;150(4):S784. https://doi.org/10.1016/S0016-5085(16)32660-9

Schoeman R, Klerk MD. Adult attention-deficit hyperactivity disorder: A database analysis of South African private health insurance. S Afr J Psychiatr 2017;23:1010. https://doi.org/10.4102/sajpsychiatry.v23.1010

Shin JY, Sohn KH, Shin JE, Park M, Lim J, Lee JY, et al. Changing patterns of adult asthma incidence: results from the National Health Insurance Service-National Sample Cohort (NHIS-NSC) database in Korea. Sci Rep 2018;8(1):15052. https://doi.org/10.1038/s41598-018-33316-y

Sol I, Kim S, Kim J, Park Y, Kim Y, Sohn M, et al. Childhood asthma analysis from the Korea national health insurance claims database. Allergy Eur J Allergy Clin Immunol 2017;72:669-70.

Esposito DB, Lanes SF, Donneyong M, Holick CN, Lasky JA, Lederer DJ, et al. Incidence and prevalence of IPF in an insurance claims database: Assessing accuracy using medical records. Eur Respir Journal 2014;44:P4113.

Wurst KE, Ephross SA. Evaluation of congenital defect rates from an insurance claims database and an electronic health record database: Comparison to US National prevalence estimates. Birth Defects Res Part A - Clin Mol Teratol 2011;91(5):390(W9).

Bahk J, Kim YY, Kang HY, Kim I, Lee J, Yun SC, et al. Using the National Health Information Database of the National Health Insurance Service in Korea for Monitoring Mortality and Life Expectancy at National and Local Levels. J Korean Med Sci 2017;32(11):1764-70. https://doi.org/10.3346/jkms.2017.32.11.1764

Yang M-S, Kim J-Y, Kim B-K, Park H-W, Cho S-H, Min K-U, et al. True rise in anaphylaxis incidence: Epidemiologic study based on a national health insurance database. Medicine (Baltimore). 2017;96(5):e5750. https://doi.org/10.1097/md.0000000000005750

Lim SS, Lee W, Kim YK, Kim J, Park JH, Park BR, et al. The cumulative incidence and trends of rare diseases in South Korea: A nationwide study of the administrative data from the National Health Insurance Service database from 2011-2015. Orphanet J Rare Dis 2019;14(1);49. https://doi.org/10.1186/s13023-019-1032-6

Loughlin J, Poulios N, Napalkov P, Wegmuller Y, Monto AS. A study of influenza and influenza-related complications among children in a large US health insurance plan database. Pharmacoeconomics 2003;21(4):273-83. https://doi.org/10.2165/00019053-200321040-00005

Tamaki J, Fujimori K, Ikehara S, Kamiya K, Nakatoh S, Okimoto N, et al. Estimates of hip fracture incidence in Japan using the National Health Insurance Claim Database in 2012–2015. Osteoporos Int 2019;30(5)975-83. https://doi.org/10.1007/s00198-019-04844-8

Kerr D, Farwell W. Incidence of serious infections among patients with ALS in a U.S. health insurance claims database. Neurol Conf 65th Am Acad Neurol Annu Meet San Diego, CA United States Conf Publ [Internet]. 2013;80(7):P07.86.

Lim D-HH, Kim Y-GJY-JG, Kim SO, Hong S, Lee C-KK, Yoo B, et al. The risk of herpes zoster in patients with ankylosing spondylitis: Analysis of the Korean National Health Insurance Service-Sample cohort database. Mod Rheumatol 2018;28(1):168-73. https://doi.org/10.1080/14397595.2017.1325034

Akhnif E, Kiendrebeogo JA, Idrissi Azouzzi A, Adam Z, Makoutode CP, Mayaka Manitu S, et al. Are our “UHC systems” learning systems? Piloting an assessment tool and process in six African countries. Health Res Policy Syst 2018;16(1):78. https://doi.org/10.1186/s12961-018-0340-y

Lagomarsino G, Garabrant A, Adyas A, Muga R, Otoo N. Moving towards universal health coverage: health insurance reforms in nine developing countries in Africa and Asia. Lancet 2012;380(9845):933-43. https://doi.org/10.1016/s0140-6736(12)61147-7

Trifirò G, Coloma PM, Rijnbeek PR, Romio S, Mosseveld B, Weibel D, et al. Combining multiple healthcare databases for postmarketing drug and vaccine safety surveillance: why and how? J Intern Med 2014;275(6):551-61. https://doi.org/10.1111/joim.12159

Pelletier KR, Marie A, Krasner M, Haskell WL. Current trends in the integration and reimbursement of complementary and alternative medicine by managed care, insurance carriers, and hospital providers. Am J Health Promot 1997;12(2):112-22. https://doi.org/10.4278/0890-1171-12.2.112

Lu Z, Su J. Clinical data management: Current status, challenges, and future directions from industry perspectives. Open Access J Clin Trials 2010;2:93-105. http://dx.doi.org/10.2147/OAJCT.S8172

Seeger J, Daniel GW. Commercial insurance databases. Pharmacoepidemiology 2012;5:189-208. https://doi.org/10.1002/9781119959946.ch13

Khan SA, Cresswell K, Sheikh A. Contextualising sehat sahulat programme in the drive towards universal health coverage in KHyber Pakhtunkhwa, Pakistan. Khyber Med Univ J 2022;14(1):63-70. https://doi.org/10.35845/kmuj.2022.21481

Sato T, Ikeda S, Noda M, Nakayama T. Development of a database of health insurance claims: standardisation of disease classifications and anonymous record linkage. J Epidemiol 2010;20(5):413-9. https://doi.org/10.2188/jea.je20090066

Hertzberg J. Disease management and disease registries: opportunities for MCOs. Manag Care Interface 2001;14(10):70,75.

Cheol Seong S, Kim Y-Y, Khang Y-H, Heon Park J, Kang H-J, Lee H, et al. Data resource profile: the national health information database of the National Health Insurance Service in South Korea. Int J Epidemiol 2016;46(3):799-800. https://doi.org/10.1093/ije/dyw253

Lechner BE. Of Tragedies and Miracles — Neonatal Organ Donation. N Engl J Med 2018;379(22):2089-91. https://doi.org/10.1056/nejmp1809147