Objective: To find out the frequency of cervical intraepithelial neoplasia (CIN) and to identify the associated risk factors in women attending outpatient department of Liaqat Memorial Hospital Kohat, Pakistan.
Methodology: This descriptive study was conducted at department of obstetrics and gynaecology, Liaqat memorial hospital Kohat from 30-10-2010 to 30-10-2011. Three hundred and sixty women, ranging in age from 20-65 years were enrolled by non-probability purposive sampling technique. Patients presenting with complaints of vaginal discharge, backache, pain hypogastrium, dyspareunia and post-coital bleeding were included. Those with diagnosed cervical cancer, visible cervical lesion/ulcer, active bleeding from the genital tract and pregnancy were excluded. Detailed history was taken. Risk factors studied were multiparity, age at first intercourse (marriage), oral contraceptive (OCP) usage, smoking, socioeconomic status and history of sexually transmitted infections. Pap smears were taken with Ayer’s spatula. Data was analyzed by SPSS version 16.0.
Results: Out of 360 cases, 12 (3.33%) had CIN with 95% CI ± 1.85(1.48%-5.I8%). In this study the mean age for the diagnosis of CIN was 35.66±6.678 years. Increased parity (75%), low socioeconomic status (58.33%), history of genital tract infection (50%) and age at marriage <18 years (41.66%) were the common risk factors in patients with CIN.
Conclusion: Cervical Intra-epithelial lesions are not uncommon. All the women above 30 years should have regular cervical screening. High parity, early marriages and poverty should be highlighted in this connection.
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