FREQUENCY OF THROMBOCYTOPENIA IN PREGNANCY RELATED HYPERTENSIVE DISORDERS IN PATIENTS PRESENTING AT TERTIARY CARE HOSPITALS OF PESHAWAR

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Rubina nazli
Mohammad Akmal khan
Tasleem akhtar
Nabila Sher Mohammad
Hina aslam
Jamila haider

Abstract

ABSTRACT

Objective: To find the frequency of thrombocytopenia in women with pregnancy related hypertensive disorders inpatients presenting at tertiary care hospitals of Peshawar.

Methodology: This cross sectional study was conducted from January 2009 to January 2010 in the tertiary referralhealth care facilities of Peshawar. A total of 312 women of gestational age of >20 weeks with pregnancy relatedhypertensive disorders were investigated. They were subdivided into 102 women with gestational hypertension (GroupA), 100 women with pre-eclampsia (Group B), and 110 women with eclampsia (Group C). Ninety healthy pregnantwomen (group D) were chosen as control. All the subjects were selected from the Gynecology and Obstetrics units ofthree tertiary health care facilities of Peshawar. Platelet count was measured by using Hematology Analyzer. The datawas processed on SPSS version 10.

Results: The frequency of thrombocytopenia in all patient groups was 21.8% (n=68/312). Individual groups showedthrombocytopenia in 14.6% (Group A), 15% (group B), 34.6% (group C) and 4.5% in controls (group D). Out of 68patients with thrombocytopenia, 38(55.9%) were eclamptic. Overall severe thrombocytopenia was recorded in 27(8.7%)patients, of whom 15(55.6%) were eclamptic. These patients were nine times more likely to have eclampsia as comparedto those having platelet count > 150,000/μL (OR: 9.41; CI: 1.33-188.8; p= 0.008).

Conclusion: A high frequency of thrombocytopenia was recorded in the patients with pregnancy related hypertensivedisorders in the tertiary care hospitals of Peshawar. The severity of thrombocytopenia is proportional to the severity ofpregnancy related hypertensive disorders.

Key Words: Pregnancy Related Hypertensive Disorders; Platelet Count; Thrombocytopenia; Gestational Hypertension,Pre-Eclampsia.

Article Details

How to Cite
nazli, R., M. khan, T. akhtar, N. Mohammad, H. aslam, and J. haider. “FREQUENCY OF THROMBOCYTOPENIA IN PREGNANCY RELATED HYPERTENSIVE DISORDERS IN PATIENTS PRESENTING AT TERTIARY CARE HOSPITALS OF PESHAWAR”. KHYBER MEDICAL UNIVERSITY JOURNAL, Vol. 4, no. 3, Sept. 2012, pp. 101-5, https://www.kmuj.kmu.edu.pk/article/view/10471.
Section
Original Articles
Author Biographies

Rubina nazli, Biochemistry Deptt.Institute of Basic Medical Sciences KMU

Dr.Rubina Nazli Associate Professor Biochemistry Deptt.Institute of Basic Medical Sciences KMU

Mohammad Akmal khan, Psychiatry Department Khyber Teaching Hospital Khyber Pakhtunkhwa Province -Pakistan

Psychiatrist Psychiatry Department Khyber Teaching Hospital Khyber Pakhtunkhwa Province -Pakistan

Tasleem akhtar, PMRC Research Centre Khyber Medical College, Peshawar Khyber Pakhtunkhwa Province -Pakistan

Center Incharge PMRC Research Centre

Khyber Medical College, Peshawar

Khyber Pakhtunkhwa Province -Pakistan

Nabila Sher Mohammad, Khyber Girls Medical College, Peshawar Khyber Pakhtunkhwa Province -Pakistan

Senior Lecturer Khyber Girls Medical College, Peshawar

Khyber Pakhtunkhwa Province -Pakistan

Hina aslam, Khyber Girls Medical College, Peshawar Khyber Pakhtunkhwa Province -Pakistan

student Khyber Girls Medical College, Peshawar

Khyber Pakhtunkhwa Province -Pakistan

Jamila haider, Frontier Women University Khyber Pakhtunkhwa Province -Pakistan

Student Frontier Women University

Khyber Pakhtunkhwa Province -Pakistan

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