Virtual reality intervention in lower limb locomotor training for patients with multiple sclerosis: a systematic review

Main Article Content

Kholood Matouq Shalabi


OBJECTIVE: To assess the results of virtual reality rehabilitation (VRR) use in locomotor training of lower limb motor skills for people with multiple sclerosis (MS).

METHODS:  This systematic review was done in accordance with the PRISMA guidelines. The literature search was done using Embase, MEDLINE, Physiotherapy Evidence Database (PEDro) and Google Scholar and articles from 1947 to 8th May 2020 were included. The keywords were “virtual reality”, “motor learning” and “Multiple Sclerosis”.  The identified studies were screened in accordance with the inclusion criteria and pertinent data was retrieved. Studies included diagnosis of MS on McDonald criteria and with use of VR for rehabilitation were included.

RESULTS:    The results included a total of 10 studies in the systematic review. These included five Randomized Controlled Clinical Trials, two prospective interventional studies, one cross-sectional study, one retrospective study, and one case series. The combined number of subjects from all studies included 376 patients diagnosed with MS. The research studies were published from 2007-2020. The review identified that VR paired with robot-assisted walk training significantly increased participants' 2-minute walk test scores and Paced Auditory Serial Addition Task scores compared to controls for the 10-meter walking test.

CONCLUSION:       Virtual reality may have positive benefits on MS patients' quality of life and lower limb learning and function along with improvements in the cognitive abilities.

Article Details

How to Cite
Shalabi, K. M. “Virtual Reality Intervention in Lower Limb Locomotor Training for Patients With Multiple Sclerosis: A Systematic Review”. KHYBER MEDICAL UNIVERSITY JOURNAL, vol. 15, no. 4, Dec. 2023, pp. 258-69, doi:10.35845/kmuj.2023.23348.
Systematic Review & Meta-Analysis


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