FACTOR-X DEFICIENCY: A RARE DISORDER TO BE LOOKED FOR IN CASES OF CONGENITAL BLEEDING TENDENCY

Abstract

ABSTRACT

Factor X deficiency is a rare, autosomal recessive disorder that involves the coagulation cascade. People with this disorder present with a myriad of early life bleeding complications. We report here a 23-year-old male, who presented with bleeding complications (prolonged bleeding from surgical wounds, unresolving hematomas, uncontrolled nasal bleeding, hematuria and hematochezia) at different stages of his life but was diagnosed very late for factor X deficiency after comprehensive evaluation for clotting factors. He was managed by repeated transfusions of fresh frozen plasma and detailed counselling. Factor X deficiency is a rare life-threatening disease and must be differentiated from other disorders of coagulation. The patients are advised to avoid activities with high levels of physical contact, unnecessary invasive interventions and drugs that remarkably affect liver functions and seek immediate medical care in case of bleeding from any site.

KEYWORDS

Hemorrhage (MeSH); Bleeding disorder (Non-MeSH); Factor X Deficiency (MeSH); Inherited (Non-MeSH); Blood Coagulation Disorders, Inherited (MeSH); Blood Coagulation Disorders (MeSH).

 

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References

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