AJWA DATE SEED IMPROVES LIPID PROFILE OF DIET INDUCED HYPERLIPIDEMIC RABBITS

Zobia Mushtaq, Samina Kausar, Naheeda Kousar, Sadia Chiragh

Abstract


ABSTRACT

Background:   Date seeds contain such constituents which can improve lipid profile. There is no study to show this effect, so it was planned to evaluate the antihyperlipedemic effect of Ajwa date seed on serum lipid levels of diet induced hyperlipidemic rabbits.

Methodology:  Male rabbits, 32 in number weighing between 0.9-1.3 kg were divided into four groups NC, HFD, HFD+2%A and HFD+4%A  having 8 rabbits each. Group NC took normal diet while all other groups were given high fat diet for whole 12 weeks. After 4 weeks groups HFD+2%A and HFD+4%A; were given diet containing Ajwa date seed powder 2gm and 4gm per 100 gm of high fat diet respectively for next 8 weeks. Lipid profile was done at 0, 4, 8 and 12 weeks.

Results: serum cholesterol, triglycerides, LDL-C, AIP and LDL/HDL ratio decreased significantly in both treatment groups along with rise in HDL-C. Initially 4% Ajwa date seed powder was more effective than 2% but at the end both were equally effective.

Conclusion: Ajwa date seeds are effective in lowering lipid levels despite high intake of fat.

KEY WORDS: High Fat Diet, Lipid Profile, Ajwa Date Seed




KHYBER MEDICAL UNIVERSITY (KMU) PESHAWAR

KMU INSTITUTE OF MEDICAL SCIENCES (KIMS), KOHAT, KHYBER PAKHTUNKHWA, PAKISTAN- 2012

 

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