CLINICAL AND DEMOGRAPHIC PROFILE OF CHILDREN HOSPITALIZED WITH MEASLES INFECTION IN PESHAWAR
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Abstract
OBJECTIVE: To record the clinical and demographic characteristics of measles in patients hospitalized with measles infection in Peshawar, Pakistan.
METHODS: A retrospective review of medical records from December 2017 to January 2016 was conducted at Northwest General Hospital and Research Centre, Peshawar. A total of 182 measles patients’ data was retrieved and recorded in predesigned format which include information on demographics, clinical features, complications and outcome. Both descriptive and inferential statistics was used for data analysis.
RESULTS: Out of 182 patients, 118(64.8%) were males. The mean age was 24.1±2.5 months. The average length of hospital stay was 3.09±2.58 days. The most common complication was pneumonia 99 (54.4%), followed by diarrhea 54 (29.7%) and encephalitis 11 (6.0%). The patients were categorized in to two age groups, pre-vaccination group (≤9 months age) and post-vaccination group (>9 months age). Significant number of cases 54 (30%) were seen in age group <9 months. Only 45 (35%) cases in age group >9 months received the scheduled measles vaccination. Multivariate regression analysis revealed that Koplik spots [AOR=0.251, Cl; 0.074-0.853, p=0.027], lymphocyte count (normal/high) [AOR=0.205, Cl; 0.092-0.453, p<0.001] and vaccination in general [AOR= 2.546, Cl; 1.185-5.469, p=0.017] were found to be significantly associated with age group >9 months.
CONCLUSION: Pneumonia was the commonest complication followed by diarrhea. Vaccination history was very poor and significant number of patients were seen in age group <9 months of age.
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