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Objective: To determine validity of myocardial perfusion imaging for the detection of coronary artery disease.
Methodology: This was a hospital based observational study, conducted in department of Cardiology, Postgraduate Medical Institute, Lady Reading Hospital, Peshawar, K.P.K, from May 2008 to Jun 2009. Myocardial perfusion imaging was performed for all patients and invasive coronary angiography was taken as gold standard for the detection of coronary artery disease.
Results: Total number of patients was 50; their mean age was 53.8±9.7 years. Men were 35 (70%) and women were 15 (30%). Myocardial perfusion imaging was reported as normal in 5(10%) patients while 45 (90%) had abnormal results. Coronary angiography showed 44 patients (88%) had > 50% stenosis in at least one coronary artery. Compared with coronary angiography, the sensitivity, specificity, positive predictive value and negative predictive values of myocardial perfusion imaging for detection of CAD were 98%, 67%, 95%, and 80% respectively. The sensitivity for the detection of ischemia in LAD, RCA, and CIRC territories were 89.7%, 94.7% and 72.2% respectively.
Conclusion: Myocardial perfusion imaging has a high sensitivity for identifying patients with coronary artery disease.
KEY WORDS: Myocardial perfusion imaging, Coronary artery disease, Coronary angiography
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