Main Article Content
This article may be cited as:Shaheen A, Khattak S, Khattak AM, Kamal A, Jaffari SA, Sher A. Serum alkaline phosphatase level in patients with type 2 diabetes mellitus and its relation with periodontitis. KUST Med J 2009; 1(2): 51-54.To study the level of serum alkaline phosphatase in diabetic patients with periodantitis and compare to control group. Material and Methods: This study was carried out in Pathology Department Gomal Medical College Dera Ismail Khan, from Jan. 2006 to June 2007. Subjects of type-2 diabetes mellitus having periodontitis (group A), diabetics without periodontitis (group B), non-diabetics with periodontitis (group C) and control subjects (non-diabetics and without periodontitis) were included. Patients of both sexes aged between 31 and 70 years were studied. Blood samples were analysed for fasting, post-prandial sugar and serum alkaline phosphatase levels. Depth of periodontal pocket >3mm was labeled as a patient suffering from periodontitis. A WHO recommended probe gently placed to the base of the pocket and the depth of insertion was read. At least six points on each tooth; mesio-buccal, mid-buccal and distobuccal and the corresponding lingual sites were measured. Patients with other diagnosed diseases affecting ALP levels were excluded. Results: No significant difference in fasting and post prandial blood sugar level in control and the non-diabetics with periodotitis. ALP showed significant rise in both diabetics and non-diabetics with periodantitis. ALP is raised slightly in diabetics without periodantitis but significantly with periodantitis (groups A & C), however, depth of pockets was very significantly more in patients with peridontitis compared to control and diabetics without periodontitis (group B). Conclusion: Periodontitis is a debilitating disease leading to significant rise in level of ALP in subjects with type 2 diabetes mellitus as well as in non-diabetics. Key words: Periodontitis, Type 2 Diabetes Mellitus, Alkaline Phosphatase.
Work published in KMUJ is licensed under a
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.