FREQUENCY OF DYSLIPIDEMIAS IN 6-12 YEARS OLD PAKISTANI CHILDREN: A CROSS-SECTIONAL STUDY
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Abstract
OBJECTIVES: To estimate the frequency of dyslipidemias in 6-12 years old Pakistani children attending pediatric clinic.
METHODS: This cross-sectional study was conducted at private clinic Peshawar, Pakistan after parental consent, on 85 (42 male, 43 female) children, with age ranging 6-12 years. Measurement of height, weight, waist circumference, body mass index (BMI), blood pressure, fasting lipid profile and fasting blood sugar (FBS) were recorded. Children with diabetes, renal or lipid disorders and their sibs, and those using metabolic profile altering medications were excluded from study.
RESULTS: About 18% of the participants were either obese (n=8, 9.5%) or overweight (n=7, 8.3%). In male children, mean BMI was 15.0±2.6 and 18.1±4.9 for 6-8 years and 9-12 years age respectively. In female children, mean BMI was 14.9±1.1 and 17.8±3.5 for 6-8 years and 9-12 years age respectively. Mean FBS was 4.5±0.5 mmol/L. Total cholesterol (mmol/L) was 3.98±.79 & 4.20±.46 for males and females of 6-8 years age and 4.27±.48 & 4.22±.54 for males and females of 9-12 years age respectively. Similarly, low density lipoprotein cholestreol (mmol/L) was 2.27±.51 & 2.53±.46 for males and females of 6-8 years age and 2.53±.50 & 2.45±.49 for males and females of 9-12 years age respectively. Eighty-nine percent of children had at least one lipid abnormality. The most prevalent lipid abnormality was low levels of high density lipoprotein cholesterol (HDL-c), borderline low or low in 75% (95% CI: 64–84).
CONCLUSION: Low level of HDL-c is the most prevalent lipid abnormality in 6-12 years old Pakistani children.
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