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Objective: To determine the effect of fit-delivery interval on maternal and fetal outcome in antenatal eclamptic patients in our set up.
Methodology: This study was conducted at Hayatabad Medical Complex Peshawar, Pakistan. All antenatal patients presenting with eclampsia from January 2011 to December 2012 were retrospectively analyzed for effect of fit-delivery interval on maternal outcome (mortality, ICU admission) and fetal outcome (meconium stained liquor, low Apgar score, still birth, neonatal ICU admission and early neonatal death). Postnatal eclamptic patients were excluded from the study. Fit-delivery interval was calculated in hours. Data were analyzed by using SPSS version 16.
Results: Out of 8558 obstetric patients, 32 (0.37%) antenatal women had eclampsia. The mean age of the patients was 24±5.36 years. Most of the patients were young (80%) and primigravida (62.4%). The mean gestational age was between 36-40 weeks. There was no maternal mortality. Three (p=0.083) patients who delivered in >15 hours after the onset of fits were admitted in the intensive care unit. Neonates who were delivered within 15 hours of onset of fits had better fetal outcome. Meconium stained liquor (12.5%, p=0.023), low Apgar score (21.87%, p=0.001) and neonatal ICU admissions (12.5%, p =0.044) were found to be statistically significant. While stillbirth (9.37%, p =0.083) and neonatal death (6.89%, p=0.161) were not statistically significant.
Conclusion: Fit-delivery interval of up to 10-15 hours had good maternal and fetal outcome. Timely referral to tertiary care hospital and timely delivery of eclamptic patients is recommended to improve the maternal and fetal outcome.
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