The purpose of this cross sectional study was to determine the frequency of under-collected 24 hours urinary samples. Diabetic patients who visited our clinic from June 2012 to November 2012 were explained the procedure for collection verbally in addition to being given written instructions. Adequacy of collection was assessed by measuring creatinine excretion rates. Out of the 112 patients enrolled, 16(14.29%) collected their samples inadequately. The education level (p< 0.001) and urine volume (p= 0.003) were lesser in these 16 patients as compared to others. Inadequate collection was common in the younger patients (22.22% patients aged less than 60 years, 6.90% aged 60 years or older ; p= 0.021). Gender (15.00% men, 12.50% women; p= 0.733) did not impact the collection of samples. Considering the high frequency of under-collections, adequacy of samples should always be checked first before proceeding further with laboratory analysis.
Heerspink HJL, Gansevoort RT, Brenner BM, Cooper ME, Parving HH,‖ Shahinfar S, et al. Comparison of Different Measures of Urinary Protein Excretion for Prediction of Renal Events. J Am Soc Nephrol 2010;21(8):1355–1360.
Polkinghorne KR. Detection and measurement of urinary protein. Curr Opin Nephrol Hypertens 2006;15(6):625-30.
Lamb EJ, Price CP. Creatinine, urea, and uric acid. In: Burtis CA, Ashwood ER, Bruns DR, eds. Tietz Fundamentals of Clinical Chemistry. St. Louis, MO: Saunders; 2008:363–372.
Shahbazian N, Hosseini-Asl F. A comparison of spot urine protein-creatinine ratio with 24-hour urine protein excretion in women with preeclampsia. IJKD 2008;2:127-31.
Aggarwal N, Suri V, Soni S, Chopra V, Kohli HS. A prospective comparison of random urine protein-creatinine ratio vs 24-hour urine protein in women with preeclampsia. Medscape J Med. 2008; 10(4): 98.
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