RISK FACTORS ASSOCIATED WITH ACUTE MYOCARDIAL INFARCTION PATIENTS ADMITTED AT THREE HEALTH CARE CENTRES OF SINDH, PAKISTAN

Bakhtyar Ali Shah, Imdad Ali Khushk

Abstract


OBJECTIVE:

To determine the risk factors of acute myocardial infarction (AMI) among adults aged >40 years.

METHODS:

A sample containing 100 cases and 200 controls were selected consecutively. Inclusion criteria for cases were patients with AMI, aged 40 years and above; while controls had patients with normal ECG interpretation, aged 40 years and above. Both gender (male/ females) were included as cases and controls. Patients with multiple admissions, with coma or critical condition or those who refused to participate in the study were excluded.

RESULTS:

Among 300 subjects, there were 156 males (52%) and 144 females (48%). Majority of subjects (52%) belonged to 40-50 years of age group. Thirty-one percent subjects were over-weight. Majority was non-smokers and carried out exercise. Majority (67.66%) also reported normal cholesterol levels. Among them, 111 (37%) were hypertensive, 23% diabetic, while 51.66% reported stress in their previous life. Males were more likely to develop AMI versus females (OR= 3.09, 95% CI= 1.50-3.10). Age group 40-50 years was also highly associated with AMI (OR= 5.36, 95% CI= 2.70-10.72). Patients who were smokers, with positive family history of cardiac diseases, hyper-cholesterol levels, hypertension, diabetes and stress and having no physical activity were more likely to develop AMI versus their controls.

CONCLUSION:

This study found that age group 40 – 50 years, male gender, over-weight, stress, hypertension and positive family history are the major risk factors for acute AMI in the study population and most of these risk factors are modifiable.  

KEY WORDS:

Acute myocardial infarction (Non-MeSH); Coronary Artery Disease (CAD) (MeSH); Risk factors (MeSH); Stress (N0n-MeSH); Pakistani population (Non-MeSH).




KHYBER MEDICAL UNIVERSITY (KMU) PESHAWAR

KMU INSTITUTE OF MEDICAL SCIENCES (KIMS), KOHAT, KHYBER PAKHTUNKHWA, PAKISTAN- 2012

 

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