AN EVALUATION OF SELECTED LIPID PARAMETERS IN PREGNANCY COMPLICATED BY GESTATIONAL DIABETES MELLITUS

Fahmida Rashid, Abdus Sattar, T A Chowdhury

Abstract


Objective:

The aim of the study was to evaluate selected parameters of lipid metabolism [serum triglyceride (TG), total cholesterol (TC), HDL-C, LDL-C] in women with gestational diabetes mellitus (GDM)

Methodology:
It was a case control study conducted in the Department of Obstetrics and Gynecology at Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine & Metabolic Diseases (BIRDEM) Hospital during the period from January 2009 to December 2009. A total of 60 pregnant (36 GDM and 24 healthy pregnant women) women at their 3rd trimester were included consecutively for the study. Data was collected by a structured questionnaire and processed and analyzed.

Result:
The glycemic status of the two groups was summarized compared and significant evidence of increased glycemia was confirmed in the GDM group in comparison with non GDM group. The lipid profile in GDM was found to be altered than those of healthy pregnant women in general. There was no statistically significant difference in serum total cholesterol, LDL-C in two comparing groups. Serum TG level was found to statistically higher and HDL-C level was statistically lower in GDM women comparing to healthy pregnant women (P<.05).

Conclusion:
The lipid profile in GDM found to be altered than the healthy pregnant women. TG level was higher in GDM and HDL-C level lower in GDM than in healthy pregnant women.

Key Words: Gestational Diabetes Mellitus, Lipids.




KHYBER MEDICAL UNIVERSITY (KMU) PESHAWAR

KMU INSTITUTE OF MEDICAL SCIENCES (KIMS), KOHAT, KHYBER PAKHTUNKHWA, PAKISTAN- 2012

 

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