@article{Shah_Lal_Haider_Ikram_Khan_2016, title={ELECTROPHYSIOLOGICAL CHANGES AFTER ELECTROCONVULSIVE THERAPY (ECT) UNDER PROPOFOL}, volume={8}, url={https://www.kmuj.kmu.edu.pk/article/view/15796}, abstractNote={<p><strong>ABSTRACT:</strong></p><p><span class="fontstyle0"><strong>OBJECTIVE</strong>: To find out the electrophysiological changes including pulse, blood pressure, Oxygen saturation and ECG after electroconvulsive therapy (ECT) under Propofol General Anaesthesia (GA).<br /><strong>METHODS</strong>: Fifty patients with Depression who underwent ECT were<br />studied. All patients were anesthetized using propofol. They were stratified according to electrophysiological changes including SPAO</span><span class="fontstyle0">2</span><span class="fontstyle0">, pulse and blood pressure at 60, 90 and 120 seconds after a course of 6 sessions of ECTs. Oxygen saturation was measured using a pulse oximeter.<br /><strong></strong></span></p><p><span class="fontstyle0"><strong>RESULTS</strong>: The age of the patients ranged from 18-60 years and mean<br />age was 45±12.02.The ranges of oxygen saturations recorded before<br />ECT was 96-100%. It was 94-97% at 60 sec, 90-92% at 90 sec, 95-98% at 120 seconds. There was initial decrease in diastolic pressure from pre - ECT (77±07) to 72±05 at 60 sec followed by increase of 73±05 at 90 sec and again coming to 74±05 at 120 sec, whereas in case of systolic pressure initial decrease of 117±06 at 60 sec, 114±04 at 90 sec and 116±07 at 120 sec. There was a decrease in mean pulse from 77±4.64 (pre - ECT) to 73±2.87 at 60 sec, 74±4.02 at 90 sec and maintaining at 74±3.52 at 120 sec after ECT procedure.<br />Out of 50 patients, 3 (6%) developed bradycardia and 2 (4%) had<br />ST-segment flattening at 60 seconds.<br /><strong></strong></span></p><p><span class="fontstyle0"><strong>CONCLUSION</strong>: ECT under Propofol is very safe modality of treatment<br />for patients with depressive illness and it gives much better and stable<br />hemodynamic changes with rapid recovery from anesthesia.<br /><strong></strong></span></p><p><strong>KEY WORDS:</strong> Propofol (MeSH), Electroconvulsive therapy (MeSH),</p><p><span class="fontstyle0">physiological parameters (Non-MeSH), Anesthesia (MeSH)</span></p><p><strong> </strong></p><p><strong> </strong></p><p><strong> </strong></p>}, number={2}, journal={KHYBER MEDICAL UNIVERSITY JOURNAL}, author={Shah, Syed Mubashir and Lal, Chooni and Haider, Zafar and Ikram, Mobeen and Khan, Muhammad Arif}, year={2016}, month={Oct.}, pages={88–90} }