FREQUENCY OF HEPATITIS B & C INFECTION IN NEWLY RECRUITED CIVIL SERVANTS IN KHYBER PAKHTUNKHWA
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Abstract
OBJECTIVE: To determine the frequency of hepatitis B virus (HBV) &hepatitis C virus (HCV) infections in healthy individuals selected fornew recruitment in civil service in various governments departmentsof Khyber Pukhtunkhwa.
METHODOLOGY: This descriptive study was carried out in Police &Services Hospital, Peshawar from 15-07-2011 to 15-10-2012. All thenewly recruited government personal (total 4639) in various cadres frombasic pay scale (BPS) 01 to 18, divided in two groups (groups-1: fromBPS 01-14 and group-2 from BPS 15-18) attending the hospital wereincluded in the study. Three millilitre of blood was subjected to rapidscreening using the Immunochrmatographic (ICT) kit. All the positivecases on the rapid screening were confirmed by 3rd Generation ELISAtechnique.
RESULTS: Out of 3012 individuals in group-1, ranging in age from 18 to30 years (mean 23.22 + 0.53 years), frequency of HBV was 4.5% & 3%,HCV was 5.2% & 3.8 % and dual HBV/HCV was 2.1% & 1.7% in malesand females respectively. While in group-2, having 1627 individuals rangingin age from 18 to 36 years (mean 24.67+ ± 0.61 years), frequencyof HBV was 2.3% & 1.8%, HCV was 2.2% & 2% while both HBV/HCVwas 0% and 0.7% in males and females respectively.
CONCLUSION: The frequency of HBV & HCV infections remains highin Khyber Pukhtunkhwa especially in the low income groups despiteapparently normal health. More extensive seroprevalance and frequencystudies recruiting various segments of the society are needed to determinethe true prevalence.
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References
Elghouhari HM, AbuRajabTamimi TI,
Chavey WD. Hepatitis B Virus infection:
Understanding its epidemiology, course
and diagnosis. Cleve Clin J Med 2008;
: 881-9.
Pertz JF, Armstrong GL, Farrington LA,
Hutin YJ, Bell BP. The contributions of
hepatitis B virus and hepatitis C virus infections
to cirrhosis and primary liver cancer
worldwide. J Hepatol 2006; 45: 529-38.
Baig S, Siddiqui AA, Ahmed WU, Qureshi
H, Arif A. Frequency of hepatitis C and D
super infection in patients with hepatitis
B related complex liver disorders. J Coll
Physicians Surg Pak 2009; 19(11): 699-703.
Ijaz AU, Shafiq F, Toosi NA, Malik MN,
Qadeer R. Hepatitis B & C in blood
donors: Analysis of 02 years data: Annals
King Edward Med Univ; 2007; 13; 59-61.
Nafees M, Farooq, Jafferi G. Frequency
of hepatitis B & C infection in general
population of Lahore, Pakistan: Biomedica
; 24: 106-11.
Ali SA, Donahue RM, Qureshi H, Vermund
SH. Hepatitis B & C in Pakistan: prevalence
and risk factors. Int J Infect Dis 2009;
(1): 9-19.
Khokar N, Gill ML, Malik GJ. General
seroprevalance of Hepatitis B and C virus
infection in population. J Coll Phys Surg
Pak 2004; 14 (9) 534-6.
Bukhari SM, Khatoon N, Iqbal A. Prevalance
of Hepatitis B antiginaemia in Mayo
Hospital, Lahore. Biomedica 1999; 15:
-91.
Qasmi SA, Aqeel S, Ahmed M, Aslam SI,
Ahmed. A detection of Hepatitis B virus in
normal individuals in Karachi. J Coll Physicians
Surg Pak 2000; 10: 467-9.
Abbas Z, Shazi L, Jafri W. Prevalence of
hepatitis B in individuals screened countrywide.
J Coll Physicians Surg Pak 2006;
(7): 497-8.
Farooq MA, Iqbal MA, Rariq WZ, Hussain
AB, Ghani I. Prevalence of Hepatitis B and
C in healthy Pakistani adults. Pak J Pathol
; 16: 42-6.
Zakaria M, Ali S, Tariq GR, Nadeem M.
Prevalance of Anti hepatitis C antibodies
and Hepatitis B surface antigen in healthy
male naval recruits. Pak Armed Forces
Med J 2003; 53: 3-5.
Shah M, Ahmed J. Prevalence of Hepatitis
B Antiginemia in general population of
Quetta, Balochistan. Biomedica 1997;
: 51-2.
Bhatti FA, Shaheen N, Tariq WUZ, Amin
M, Salim M. Epidemiology of Hepatitis C
virus in blood donors in Northern Pakistan.
Pak Armed Forces Med J 1996; 46: 19-20.
Masood Z, Jawaid M, Khan RA, Rehman
SU. Screening for hepatitis B and C: A
routine preoperative investigation? Pak J
Med Sci 2005; 21(4): 455-9.
Chien-Jen C, LI-YU W, Ming-Whei Y. Epidemiology
of Hepatitis B virus infection
in Asia Pacific region. Towards control of
Hepatitis B in Asia Pacific region. J Gastroenterol
Hepatolo 2000; 15: Suppl: E3-6.
Alter MJ; Epidemiology of Hepatitis C virus
infection: World J Gastroenterol; 2007: 13
(17): 2436-41.
Bhatti MS, Qureshi M, Mahood CZ, Junaid
K. Seroprevalance of HBsAg and Anti HCV
antibodies in healthy individuals of high
socioeconomic status. Biomedica 2007;
: 131-3.
Mirza IA, Mirza SH, Irfan S, Siddiqi R, Tariq
WUZ, Asif. Seroprevalance of Hepatitis B
and C in young adults seeking recruitment
in armed forces. Pak Armed Forces Med J
: 56(2): 192-7.
Aziz MS. Prevalence of Anti Hepatitis C
antibodies and Hepatitis B surface antigen
in healthy blood donors in Baltistan. Pak
Armed Forces Med J 2006; 56(2) 189-91.
Butt T, Amin MS. Seroprevalance of hepatitis
B & C infections among young adult
males in Pakistan. East Meiterr Health J
; 14 (4): 791-7.